Cancer is a major cause of death worldwide justifying a concerted effort for basic and applied research. Cancer involves multiple pathogenic pathways. For example, a progressive metabolism reprogramming favours tumour growth and dissemination in most cancers. Moreover, the tumor itself can exert systemic deleterious effects on the body, e.g. immunosupression. Patient treatment and survival can be severely compromised unless we understand these metabolic and systemic effects.
UMR9018 "Metabolic and systemic aspects of oncogenesis for new therapeutic approaches" (METSY) is located on the campus of the Gustave Roussy Institute in Villejuif. The unit is composed of three teams and 40 researchers, technicians, postdoctoral fellows and doctoral students working on the different aspects of cancer and oncogenesis.